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247031 Part A


Study Dates: Screening will take place throughout 2021 - please call 01895 614 888 for the latest screening days and times.

Trial Number

247031.1

Group

●  Healthy Volunteer
●  Smoking (No)
●  Non-Childbearing Females

Compensation

Up to: $2,217

Gender

Male, Female, Non-Smoker

Age

18-55

BMI

18-30

Additional Information

This study consists of a screening visit, a PCR visit, 7 nights in-house and a single follow-up phone call. The study requires Healthy Males & Non-childbearing Females aged 18-55.

Details

The Study drug is being developed to treat patients who suffer from a disease known as Multiple System Atrophy (A fatal neuro-degenerative disorder where brain cells progressively die leading to loss of many body functions, including breathing and eating. There's currently no cure for multiple system atrophy and no way of slowing its progression.)

This

trial is looking to determine:

· The

safety and tolerability of the drug in humans.

· How

it is distributed, broken down and excreted from the body.

The

drug will be administered in the form of a tablet with a glass of water.

This is a First In Human Study.